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In women with metastatic breast cancer, a new medicine doubles their chances of survival.

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Trastuzumab is an example of inventiveness in the history of little incremental triumphs in the fight against cancer. The new study was led by a team from the International Breast Cancer Center (IBCC) in Barcelona. The country of Spain is depicted in this photograph. The medication trastuzumab deruxtecan was investigated in the Destiny Breast-03 clinical study in patients with HER2-positive metastatic breast cancer, a particularly aggressive subtype of malignant tumours that affects 20% of patients. The medicine, dubbed a Trojan horse by the researchers, mixes a targeted drug (trastuzumab) with a chemotherapeutic treatment (deruxtecan). The first precisely hits the malignant cells, where the HER2 protein is produced, which is responsible for the tumor's rapid progression. When compared to another similar combination, trastuzumab with emtansine, which is now the conventional treatment when patients with these cancers stop responding to the first line, the effects of this medicine sh...
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Natural immunity and the risk of SARS-CoV-2 reinfection and hospitalisation with COVID-19

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 A new Swedish study looks at the protective effect of natural infection immunity versus hybrid immunity in the context of the ongoing coronavirus disease 2019 (COVID-19) pandemic, which has excellent vaccine coverage in several locations but growing rates of new infections in particular hotspots. Introduction  There has been substantial debate about whether people with a prior COVID-19 infection should be vaccinated against the severe acute respiratory syndrome coronavirus 2. (SARS-CoV-2). The injection of a COVID-19 vaccine often results in an immunological response, demonstrating that vaccination is still helpful. The job of persuading patients with prior infection to take a first series of the vaccine, including boosters, is rendered more challenging in the absence of hard evidence. With vaccine passports becoming a requirement in some countries, significant disparities in the approach to issue these passports have emerged. Should only individuals with hybrid immunity be c...
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The goal of the smart bra is to speed up the diagnosis of breast cancer.

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According to the creator, a smart bra developed in Nigeria can identify breast cancer early, potentially saving African women extensive treks to seek screening services. In Sub-Saharan Africa, breast cancer is the most frequent type of cancer among women, with 129,000 new cases expected in 2020. According to the World Health Organization, only around half of women in this country live for more than five years after being diagnosed, with late diagnosis being a major cause (WHO). Kemisola Bolarinwa, a robotics engineer who designed the smart bra, expects it can help overcome barriers to early detection of the disease. Bolarinwa, the creator of Nextwear Technology, a wearable technology firm situated in Abuja, Nigeria, says, "My loving mother died of breast cancer in 2017 at the University College Hospital in Ibadan, Nigeria, because it was diagnosed late." "I observed ladies of all ages, including teenagers, writhing in pain from breast cancer in her hospital ward. That...
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Early detection and differential diagnosis of Parkinson's disease can be aided by a skin biopsy.

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Parkinson's disease (PD) is currently diagnosed using clinical criteria that have been agreed upon. The presence of neuronal deposits of the biomarker phosphorylated alpha-synuclein (p-syn) in the brain and skin of patients with PD distinguishes them from individuals with symptoms of parkinsonism due to the accumulation of another protein, tau, according to a new study published in the Journal of Parkinson's Disease. This advancement could aid in the early detection and differentiation of Parkinson's disease among the numerous parkinsonism subtypes. Other synucleinopathies, as well as atypical parkinsonism, such as progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS), both of which are caused by the buildup of another protein, tau, share the core parkinsonian symptoms. Despite their clinical similarities, PSP is distinguished by 4-repeat tau deposits, which are found primarily in the basal ganglia, brainstem, and cerebellum, while CBS is a clinical syndrome ...
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Doctors explain why a high-salt, high-protein diet is bad for your kidneys.

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Kidney illness affects one out of every ten persons on the planet : Kidneys are bean-shaped organs in the human body that filter water and waste while also regulating minerals and nutrients in the blood. Kidneys are one of the body's important organs that assist manage blood pressure, regulate red blood cell formation, and determine the general health of the bones. Every year on the second Thursday in March, World Kidney Day, a joint initiative of the International Society of Nephrology (ISN) and the International Federation of Kidney Foundations (IFKF), is observed to raise awareness of the importance of kidneys and to reduce the global impact of kidney disease and its associated health problems. The 10th of March is World Kidney Day this year. According to a government report, renal illness affects one out of every ten persons worldwide. How do the kidneys keep the human body in check : Apart from the well-known function of the kidney in removing excess waste and fluid from the ...
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According to a new study, blood types play a vital impact in whether or not patients acquire severe COVID-19.

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Over 3000 proteins were evaluated in a new study to see which were causally associated to the development of severe COVID-19. This is the first study to look at so many proteins to see if they're linked to COVID-19. The findings point to potential new targets for COVID-19 treatment and prevention strategies. The study, which was supported in part by the National Institute for Health Research (NIHR) Maudsley Biomedical Research Centre, employed a genetic technique to screen over 3000 proteins and was published in PLOS Genetics. Researchers discovered six proteins linked to an elevated risk of severe COVID-19 and eight proteins linked to protection against severe COVID-19. Blood types are determined by one of the proteins (ABO) that has been linked to the likelihood of acquiring severe COVID-19, implying that blood groups play an important role in whether people get severe forms of the illness. Dr. Alish Palmos of King's College London's Institute of Psychiatry, Psychology, a...
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Long-term COVID symptom: This skin sensation can last for months.

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The World Health Organization (WHO) emphasised last week that long COVID hazards are real, and that such difficulties will be a part of our future regardless of the variation one has been infected with. More details about the symptoms and severity of the disease are emerging as more research is undertaken on the subject. According to recent studies, post-COVID sequelae increase the risk of heart disease, vasculitis, and other serious disorders. Aside from the more well-known symptoms of brain fog, shortness of breath, and loss of smell and taste, many patients are also reporting skin problems that should be taken seriously. What are the signs and symptoms of long-term COVID on the skin?  Many people who have been infected with COVID have reported a tingling feeling on their skin after they have recovered. If they have been sitting in the same position for a long time, such patients report prickling, tingling, or numbness. The sensations in the hands, arms, legs, and feet are intens...
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