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Showing posts from April, 2022

In women with metastatic breast cancer, a new medicine doubles their chances of survival.

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Trastuzumab is an example of inventiveness in the history of little incremental triumphs in the fight against cancer. The new study was led by a team from the International Breast Cancer Center (IBCC) in Barcelona. The country of Spain is depicted in this photograph. The medication trastuzumab deruxtecan was investigated in the Destiny Breast-03 clinical study in patients with HER2-positive metastatic breast cancer, a particularly aggressive subtype of malignant tumours that affects 20% of patients. The medicine, dubbed a Trojan horse by the researchers, mixes a targeted drug (trastuzumab) with a chemotherapeutic treatment (deruxtecan). The first precisely hits the malignant cells, where the HER2 protein is produced, which is responsible for the tumor's rapid progression. When compared to another similar combination, trastuzumab with emtansine, which is now the conventional treatment when patients with these cancers stop responding to the first line, the effects of this medicine sh

Natural immunity and the risk of SARS-CoV-2 reinfection and hospitalisation with COVID-19

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 A new Swedish study looks at the protective effect of natural infection immunity versus hybrid immunity in the context of the ongoing coronavirus disease 2019 (COVID-19) pandemic, which has excellent vaccine coverage in several locations but growing rates of new infections in particular hotspots. Introduction  There has been substantial debate about whether people with a prior COVID-19 infection should be vaccinated against the severe acute respiratory syndrome coronavirus 2. (SARS-CoV-2). The injection of a COVID-19 vaccine often results in an immunological response, demonstrating that vaccination is still helpful. The job of persuading patients with prior infection to take a first series of the vaccine, including boosters, is rendered more challenging in the absence of hard evidence. With vaccine passports becoming a requirement in some countries, significant disparities in the approach to issue these passports have emerged. Should only individuals with hybrid immunity be considered